I'd interview them. I have never turned anyone down for having a degree. It's just that you don't need a degree to get started in my field, so I commonly run into things like 4 year degree vs dude who's been doing help desk 6-12 months, and I'd take the help desk guy any time.
But if we are looking at two candidates with the Same experience, but one has a degree, the degree will get you in the door for an interview, but when it comes to the hiring decision, I'm primarily going to be looking at personalities rather than the degree.
The degree can still help these days. But it's limited. It used to be that you needed one to get into a lot of the professional world, not that long ago. These days, in my field at least, not so much. But it might get your resume noticed, and you might be able to negotiate a little better salary. But the common thought is that a little experience is better.
I'd say the best place it helps is the least way people want to use it: go get a degree and start off in help desk. You with no experience but a degree, vs someone with no experience or degree? You win that one. Then you'll have the experience and degree later down the line. People these days though, want to get the degree and jump right into the better engineer/administrator roles, and expect senior pay for it. Then claim their degree is useless when that doesn't work.
All the degree does is give you a slight edge over some other candidates.
