China Wuhan Virus Pandemic

[Vyor]

Covid neither causes your immune system to chew a hole in your stomach linIng nor your arterial wall. It certainly doesn't pass the blood brain barrier. Nor does it cause meningitis from lesions in the meninges. But you know what does? Auto immune response to spike proteins on your own cells.

Your "better explanation" doesn't even fit the data.

So getting the virus would do those things to people as well, got it.

 

[Iconoclast]

@Vyor
You don’t even have a single friggin’ clue what’s happening here. Nobody in this thread does. You think you've seen a "Gish Gallop" from me? I have barely even skimmed the surface. Once you see the whole picture, it quickly becomes apparent what’s really happening here, and how it has been planned out since the 1970s, and possibly for much longer than that.

I’m not gonna bother putting any link spam in this post. I want people to actually read this from end to end and not get sidetracked on a Wiki Walk looking over a ton of references. If you think something I say here is wrong, feel free to Google it. In fact, I wholeheartedly encourage it.

Back in 1968, Paul R. Ehrlich published a book entitled The Population Bomb. It was a Malthusian treatise about how the Earth was massively overpopulated and we were due for mass starvation in a decade or two if nothing was done. His predictions were wrong. Dead wrong. New technologies like the widespread adoption of synthetic fertilizer, pesticides, and GMO plant strains allowed for the continued expansion of agriculture well beyond what he imagined possible.

However, Ehrlich’s deranged mutterings about the necessity of depopulation and degrowth became fashionable among the super-rich who grew paranoid of the Earth’s billions eating the foundations of their palatial mansions like termites. Aurelio Peccei, Alexander King, and David Rockefeller founded the Club of Rome the same year Ehrlich’s book was published. The Club of Rome commissioned the infamous MIT World3 study that projected total collapse of society by 2040 due to resource shortages and overpopulation.

If you read stuff written by George Monbiot, Kate Raworth, Herman Daly, and other Greens, they very rarely mention atmospheric CO2 in their writings.

This is what Greens talk about among themselves:

• Ozone Depletion
• Soil Erosion
• Aquifer Depletion
• Habitat Loss
• Ocean Acidification (and associated Coral Reef loss, with cascading effects on fish stocks)
• Nitrogen and Phosphorus Runoff
• Peak Oil
• Peak Natural Gas
• Peak Minerals (including phosphate minerals for fertilizer, but particularly those minerals needed for tech)

Greens take this shit very, very seriously. They believe, almost religiously, that the Earth has only another 60 years of usable topsoil for agriculture, and the United Nations and their reports concur with them on this. This is literally what the FAO say about it. Go look it up.

Does the media talk about this? No. Never.

This is what the media talks about instead:

• Atmospheric CO2 levels
• Nothing else, just CO2
• Just CO2, all the time
• You have to do something about your CO2
• Maybe breathe less, or buy an electric car, we don’t know

There are very specific reasons why this is the case.

1. The CO2 narrative of sustainability allows the problem to be framed as an outside threat. If people are made aware of the other aspects of the Green agenda (see the more complex list above), it makes it rather obvious that human beings themselves are the problem. CO2 literally sounds like just something wrong with the air around us. It obfuscates the supposed problem of overpopulation.
2. It creates a simplified narrative that is easy for average people to grasp and which generally achieves the degrowth goals desired by the Overclass. After all, lower CO2 output means, generally, lower metrics of human activity in a broad-spectrum manner, which handily takes care of the aquifer and soil erosion problem, too, but also starves people to death like the Holodomor.
3. It creates an ecosystem of fake “green tech” that doesn’t work as advertised, from wind turbines that take gargantuan amounts of steel, copper, and concrete to construct, to solar panels that require semiconductor factories to spew toxic black lakes of poison, which are all basically non-recyclable and create heaps of toxic waste at the end of their lifespans, and also require continuous investment.
4. It acts as the impetus for a system of “carbon credits” which allows for the financialization of carbon sinks via “natural asset companies” that convert government subsidies for nature conservation efforts into someone else’s private profits.

In the Club of Rome’s 1991 publication, The First Global Revolution, there is a quote that reads as follows:

In searching for a common enemy against whom we can unite, we came up with the idea that pollution, the threat of global warming, water shortages, famine and the like, would fit the bill. In their totality and their interactions these phenomena do constitute a common threat which must be confronted by everyone together. But in designating these dangers as the enemy, we fall into the trap, which we have already warned readers about, namely mistaking symptoms for causes. All these dangers are caused by human intervention in natural processes, and it is only through changed attitudes and behaviour that they can be overcome. The real enemy then is humanity itself.

The people pushing the nonsense about CO2 know exactly how unpopular this sentiment is.

“Oh my god, humans are just these overgrown locusts eating everything, whatever shall we do? These pests! Smush them before they eat my limousine!”

I cannot tell you how many times, on SpaceBattles, I raised the issue of sustainability only to be mocked by Gamesguy and his friends incessantly, or hear facile rejoinders about "manufacturing topsoil" from people who don't even vaguely grasp the logistics of manufacturing and distributing billions of metric tons of anything.

Now, Net Zero is everywhere. Everywhere you look, there is some talking head mumbling something about how we need an "Economic Reset", or "15-minute cities", or to re-wear the same shirt for a year, or whatever. There are Extinction Rebellion morons dousing paintings in the Louvre with soup and lying down in front of ambulances.

If the people who gave me nothing but constant shit ten years ago had half a brain, they would come forward, apologize for all the bullshit they slung at me, and admit that my concerns were prescient. There has never been a bigger I told you so in the history of any of these boards than me calling the Circular Economy a whole fucking decade before anyone else gave a shit.

Thanks to Kissinger and his ilk, population control is practically the policy of the US Government. If you doubt this, then go read National Security Study Memorandum 200 (a.k.a. the Kissinger Report), the Jaffe Memo, and the New Order of Barbarians transcripts. The Rockefellers were and are also heavily involved in literally every part of this. John D. Rockefeller III founded the Population Council in 1952 to implement contraceptives and family planning everywhere.

If that didn't work to stem the human tide, then they planned more extreme measures in succession:

• Push single-family home ownership outside the reach of the average person and end single-family zoning.
• Divide women from men by pushing them into the workforce and making them too busy and stressed out to reproduce. This would also increase tax revenue and make labor cheaper for giant corporations by creating an artificial supply glut of new bodies.
• Encourage promiscuity, contraceptives, and abortion to prevent stable family relationships from forming.
• Promote homosexuality and transgenderism as a form of contraception, without giving one solitary shit about how disruptive to society this is or about the actual wellbeing of LGBT people.
• Make people's children into effective wards of the State to brainwash them before they have a chance to internalize values that might encourage them to start a family later in life.
• If those tactics didn't work, then use bioweapons to cull the herd as a last resort.

Guess which stage we're at?

Literally everything dysfunctional about modern society is a product of population control measures. Can't afford a house? Silly plebeian, what were you planning to do in that house? Breed? With a member of the opposite sex? Not on your life.

Incels running around everywhere, begging to know when they get their turn to at least touch a woman's tits, are actually a symptom of successful population control measures that have kept the sexes apart. Our present-day society is, in a sense, a direct, intended product of Title IX and college sex panics that have framed human males in a hilariously dehumanizing manner as terrifying neanderthal hump-beasts who want to impregnate everything in sight.

The Overclass know exactly how destructive all of this is to the fabric of society. They monitor it. They have social scientists and expert psychologists constantly studying this and coming up with strategies to redirect people's very basic, very understandable resentment at being shut out of life itself into distractions, trinkets, baubles, video games, hard drugs, literally whatever they can do to sedate and stupefy people while they keep FUCKING STEALING FROM US UNIMPEDED.

Klaus Schwab was handpicked by Henry Kissinger in 1971 to lead the European Management Forum, which was later renamed the World Economic Forum. The purpose of the European Management Forum was right in the name. To manage the economy and population of Europe, mostly in directions that would be satisfying to Kissinger, the Rockefellers, the Rothschilds, et cetera. They changed it to the World Economic Forum to make it sound more inclusive, less paternalistic, and less on-the-nose about their disgusting ambitions to "Manage Europe".

Around this same time, the Bretton Woods system collapsed and the USD became a completely fiat currency. The purpose of this financial transformation was to render the US economy and population easier to control. The Overclass were very upset that the post-war US was so prosperous and that so many newly wealthy people were running around threatening to supplant the old dynasties, so they decided to put their thumb on the scale and shift income away from labor and toward speculators. Unsound money was just a foot in the door to spend the next fifty years dismantling US industry and shipping it all off to China.

This is the pattern they use:

1. Use globalization to access cheap sweatshop labor.
2. Force domestic industry to compete with overseas industry in countries with a far cheaper cost of living.
3. Buy up bankrupt domestic companies, liquidate them, and cancel all their workers' pensions (particularly factories, steel and aluminum production, etc.).
4. Shift the economy toward R&D and services, which, in turn, requires higher credentials, which, in turn, requires college brainwashing and the associated debt servitude of student loans.
5. The disciplining of labor that results from this process essentially forces people to do most of their consumption on credit instead of paying cash for things, further enriching the looters.

And, just like that, you have:

• Debt peonage due to the credit trap from stagnant wages versus a rising cost of living.
• A loss of institutional knowledge among the skilled trades.
• Increased urbanization.
• A growing wealth gap.
• Assets being stripped away and given to a smaller and smaller pool of rentiers.
• A bunch of angry Marxists running around demanding a dole to make up for the lost wages.

This is a perfect recipe for demolishing and looting a country and keeping average people too harried, too tired, and too poor to start and raise families.

In 1970, Zbigniew Brzezinski published a book entitled Between Two Ages: America's Role in the Technetronic Era. This book contained accurate, prescient depictions of what the coming internet and new media would do to our culture and laid down a blueprint for the forthcoming dystopia. In 1973, David Rockefeller and Zbigniew Brzezinski founded the Trilateral Commission. If you can't comprehend why the existence of the Trilateral Commission was and still is a bad thing, then you should read their report, The Crisis of Democracy, by Michael Crozier, Sam P. Huntington, and Joji Watanuki, which should make it abundantly clear that the Overclass utterly despised it that average people got a vote that was worth a shit.

In case you're too lazy to read the whole report, this quote from it should set the stage:

At the present time, a significant challenge comes from the intellectuals and related groups who assert their disgust with the corruption, materialism, and inefficiency of democracy and with the subservience of democratic government to "monopoly capitalism." The development of an "adversary culture" among intellectuals has affected students, scholars, and the media. Intellectuals are, as Schumpeter put it, "people who wield the power of the spoken and the written word, and one of the touches that distinguish them from other people who do the same is the absence of direct responsibility for practical affairs."

In some measure, the advanced industrial societies have spawned a stratum of value-oriented intellectuals who often devote themselves to the derogation of leadership, the challenging of authority, and the unmasking and delegitimation of established institutions, their behavior contrasting with that of the also increasing numbers of technocratic and policy-oriented intellectuals.

In an age of widespread secondary school and university education, the pervasiveness of the mass media, and the displacement of manual labor by clerical and professional employees, this development constitutes a challenge to democratic government which is, potentially at least, as serious as those posed in the past by the aristocratic cliques, fascist movements, and communist parties.

In addition to the emergence of the adversary intellectuals and their culture, a parallel and possibly related trend affecting the viability of democracy concerns broader changes in social values. In all three Trilateral regions, a shift in values is taking place away from the materialistic work-oriented, public-spirited values toward those which stress private satisfaction, leisure, and the need for "belonging and intellectual and esthetic self-fulfillment." These values are, of course, most notable in the younger generation. They often coexist with greater skepticism towards political leaders and institutions and with greater alienation from the political processes. They tend to be privatistic in their impact and import.

The rise of this syndrome of values is presumably related to the relative affluence in which most groups in the Trilateral societies came to share during the economic expansion of the 1960s. The new values may not survive recession and resource shortages. But if they do, they pose an additional new problem for democratic government in terms of its ability to mobilize its citizens for the achievement of social and political goals and to impose discipline and sacrifice upon its citizens in order to achieve those goals.

"Oh no, the disenfranchised young people shoved aside by our professional-managerial class drones prefer leisure and aesthetics to slavery! Quickly! Deny them a political voice before they change anything too drastically for our rich masters' tastes!"

Essentially, the report argued for more centralization of power, and shifting away from competing party interests to what we have today, which is a neolib-neocon uniparty blob that serves a shadowy and unaccountable administrative state. Patrick Wood documented this transformation in his writings (Trilaterals Over Washington, Technocracy Rising: The Trojan Horse of Global Transformation, Technocracy: The Hard Road to World Order, The Evil Twins of Technocracy and Transhumanism, and so forth, which are all heavily suppressed books). In Samuel T. Francis's book, Leviathan and its Enemies, he explains how the managerial elites rose to prominence over the latter part of the 20th century and displaced the old order. Adam Curtis described the effects of this in his documentary for the BBC, Hypernormalisation, which outlines exactly how modern democracy is basically just kayfabe for a gullible public who still think their vote makes a difference, and all the real power is held by technocrats running a Truman Show-like simulacrum of democracy.

Technocracy and its sibling Managerialism are why we have all these problems that we do today. The only reason why these systems of governance exist is to keep the public at bay while the Overclass - the extractor class, who produce nothing and arrogate to themselves every scrap of life and soil and all the mineral resources on this Earth - run off with all the tangible wealth and leave the rest of us with nothing.

This belief system, which is neither capitalist nor communist, but a hybrid of both, is aimed at grasping and seizing all real wealth and creating a prison planet of helpless and propertyless debt-serfs living in a neofeudalist hell. It blends the worst parts of capitalism with the worst parts of communism, at once applying market incentives to bureaucracy and central planning to the flow of wealth.

The capitalism versus communism debate is kayfabe. It's a manufactured crisis. These ideologies are both two sides of the same exact materialist coin. They both posit that human life has no intrinsic value and that it is only valuable insofar as it can provide labor. They both result in various forms of monopoly power - either a plutocracy of the landed rich, or the seizure and holding of the means of production by the State - both of which are deeply destructive to the common life.

Technocracy denies the value and roles of the aesthetic, the spiritual, the domestic. All things are subordinated to the factors of production. This is why we live in crackerbox condos and work in depressing, formless steel and glass cubes, deliberately designed to wear down and abuse the human mind, body, and spirit. So soulless and artless and bereft of any understanding of beauty is the modern life, people have started hallucinating past civilizations that never existed, giving rise to urban legends of a "Lost Tartaria" that are founded on little more than grainy photos of century-old World's Fair buildings made out of plaster staff.

Modern society is the result of a century-long campaign of mass psychological warfare and mass poisoning that has produced poor, decrepit, obese, indolent, sexually confused, Stockholm Syndrome-afflicted specimens of humanity too stupid and too inert to realize that they're being caged like battery hens and abused by psychopaths. Look at how the media recoil with horror at RFK Jr.'s nomination to lead HHS and take unnecessary additives, colorings, and seed oils out of food. Do you know who initially studied how to poison populations by interfering with food quality? The CIA, under Project MKNAOMI, the lesser-known sister program of MKULTRA. We let giant agribusinesses get away with lining their pockets by selling filtered and bleached industrial lubricants as fucking food, which is why everyone in the US is fat and sick and suffers from chronic inflammation.

The reason why this nonsense continues unchecked is because it has been slowly normalized by decades of frog-boiling. Imagine explaining all of this to someone with a straight face. The Overton Window has been shifted so far away from reality that it's not even in the same zip code as any of this.

In the 1970s, the Biological and Toxin Weapons Convention was ratified by numerous countries, including the US. When Nixon ended the US offensive biological warfare program in 1969, US bioweaponeers were furious that they didn't get to play around willy-nilly in laboratories with deadly pathogens anymore. They bragged that they had perfected the art of killing as many human beings as possible, as gruesomely as possible, for pennies on the dollar. If you look in BMJ, on the Economics of Bioweapons, it was shown that the comparative cost per square kilometer for various weapons to kill human beings was $2000 for conventional weapons, $600 for nuclear weapons, and $1 for bioweapons. In that same article, it was also estimated that one would need a mere 100 kilograms of aerosolized anthrax released upwind to massacre the entire population of Washington, D.C. in one go.

The BTWC had a loophole, however. It allowed for "defensive" bioweapon research to continue where offensive bioweapon research left off, which gave rise to the practice of "biodefense". Biodefense research is fundamentally the same as offensive bioweapon research. In both instances, you are taking a pathogen and making it more lethal and transmissible, hence "Gain of Function" research, or "Dual-Use Research of Concern" (GOF/DURC). This euphemistic framing of bioweapon research as defensive in nature does not preclude accidental laboratory leaks, nor does it preclude illegal, clandestine deployment of lab-enhanced pathogens produced ostensibly for defensive purposes. So, in short, the BTWC did jack shit to stop bioweapon research. Everyone just kept producing bioweapons anyway, but they called it something different.

Bioweapons should not exist. They are weapons of the rich, to be used against the poor, to clean out excess population while leaving infrastructure intact, unlike nukes or conventional ordnance. The Overclass would never actually allow their production to be prohibited comprehensively because that would mean they'd lose the perfect opportunity to inexpensively cull large swaths of the world's population.

In 1991, the Nunn-Lugar Act was passed, which started the Cooperative Threat Reduction program. The CTR was led by the Defense Threat Reduction Agency, and its ostensible purpose was to find, disarm, and destroy (essentially, EOD work) post-Soviet WMDs before they fell into the hands of terrorists and tin-pot dictators. It seemed a noble goal, on the surface. In reality, it allowed DTRA and DARPA to sink their tendrils into biolabs all over the globe, sending people like Michael Callahan into post-Soviet biolabs to help the Russian Federation (this was the early 2000s) document, patent, and commercialize all the stuff the Reds developed during the Cold War, including novel small-molecule drugs and the like. This was called the BioIndustry Initiative or BII.

Through programs like BII, and the CBEP/BTRP, DTRA and DARPA slowly wormed their way into biolabs in Ukraine, Kazakhstan, Uzbekistan, Georgia, Azerbaijan, Jordan, Iraq, Afghanistan, Pakistan, Laos, Cambodia, the Philippines, and so on. The Lugar Center in Tbilisi is actually named for Richard Lugar. Richard Lugar was buddies with Sam Nunn and Ted Turner, who founded the Nuclear Threat Initiative. Ted Turner is a rich Neo-Malthusian, like Bill Gates, who thinks the planet is overpopulated with an excessive number of human locusts. Dilyana Gaytandzhieva, a Bulgarian journalist, documented how pathogens were being moved to and from the Lugar Center in cars bearing diplomatic markings, as well as other sinister goings-on at the lab.

@Bacle, you think the Ukrainian biolabs aren't a problem. You think the wealthy, Malthusian, human-hating oligarchs funneling public money into GOF/DURC research aren't a problem. You're unfortunately mistaken. If Wuhan was a problem, then so is Ukraine. So is the Lugar Center. So are the rest of the DTRA and DARPA-associated foreign biolabs. It's the same network. The same people. DTRA having a presence in these labs to monitor them and prevent unwanted biological research by using the CBEP/BTRP as a jobs program for Ukrainian scientists does not preclude such a connection having a dual purpose, such as the CIA conducting clandestine operations, like weaponizing and surreptitiously deploying agents developed in these labs. Dr. Robert Redfield, formerly head of the CDC, has seen the classified intel, and he has stated, unequivocally, that there is a possibility that SARS-CoV-2 wasn't even synthesized in Wuhan, but at Ralph Baric's lab at UNC Chapel Hill, or at Fort Detrick, which implies that the supposed "lab leak" in Wuhan may have been staged by the CIA to pin the blame on China. However, I am getting ahead of myself.

Also, don't get me started on rich people. I don't want to hear any fucking sob stories about, "Oh, the poor billionaires". They rape little kids. On a practically industrial scale. If you don't think so, then feel free to go read the Dutroux X-Dossiers, which detail human hunting parties held in old Belgian castles where rich sickos would pursue young kids through the woods with hunting dogs like fucking pheasants. The Khashoggis were good friends with the Belgian elite human trafficking network, which is why I didn't shed one single tear when Jamal Khashoggi got chopped up in the Saudi consulate in Istanbul. The Khashoggis are a crime family. Every single one of them. Fuck them all.

In 1992, in Rio de Janeiro, at the Earth Summit, the representatives of a bunch of rich assholes got together, introduced Agenda 21 (which later morphed into Agenda 2030 and the Sustainable Development Goals), and decided how the natural world would be parceled out. This would be, essentially, enclosure on steroids. On the surface, it seems like a wonderful, noble, green sustainability initiative, but it's pure bullshit aimed at turning rainforests, mangroves, wetlands, and other uninhabitable stretches of land into securities for rich cocksuckers to exploit, and to funnel taxes into conservation efforts that would improve these "assets". Privatized gains, socialized losses. The whole CO2 sink malarkey is pretty much exclusively for the purpose of running this financial scam while also diminishing people's living standards by dismantling productive industries to reduce "carbon footprints".

Throughout the 1990s, the US Army inoculated troops against Anthrax, giving them Gulf War Syndrome, and they blamed it on exposure to DU, burn pits, armored vehicle exhaust, and just about anything else other than the vaccines that gave these unfortunate men and women chronic inflammatory and autoimmune disease. This scam was run by Robert Kadlec, his buddy Fuad El-Hibri, and the company BioPort (later known as Emergent BioSolutions). Their sister company, DynPort, was a spinoff of Porton in the UK and DynCorp. DynCorp is a mercenary company implicated in human trafficking in Bosnia and Afghanistan; their procurement of underage girls for prostitution and the habitual raping of young children in Bosnia was the topic of the film The Whistleblower, which was about the real-world investigator Kathryn Bolkovac who was attached to DynCorp and caught them in the act.

Let me just add, Madeleine Albright was an enormous piece of fucking shit who deserves to have her grave pissed on for all eternity, because she looked the other way while DynCorp did all of this.

Jeffrey Epstein's flight logs from New Mexico list off a Bell 206L-3 helicopter with the tail number N474AW. If you look this up in the FAA's tail number registry, there is no such helicopter. Actually, this tail number belonged to an OV-10 Bronco crop duster owned by DynCorp which they'd leased from the US State Department for coca eradication in Colombia, flying over coca crops and spraying carcinogenic RoundUp, often overspraying and hitting adjacent food crops and the workers on them. This particular OV-10 was involved in an accident. You can look up the accident report yourself, if you want. It had an engine failure and rammed into a mountainside three miles from Caquetá. The pilot ejected safely.

What this means is that, for one thing, Jeffrey Epstein was riding in an aircraft with a forged tail number, which is highly illegal (it's like having a fake license plate on your car), and also, that the US State Department was likely involved. With a helicopter using a diplomatic tail number, Epstein would've been able to cross borders all day long.

Jeffrey Epstein was a Mossad and CIA asset. His job was to blackmail Western dignitaries to put them under the thumb of Mossad and the CIA by filming them fucking kids on his island. Epstein was a close associate of Lynn Forester de Rothschild and Ehud Barak. His mentor, Robert Maxwell (born Ján Ludvík Hyman Binyamin Hoch) was a longtime Mossad asset. Maxwell was the guy who sold out Mordechai Vanunu for giving away Israel's nuclear secrets. He was also involved in the Inslaw PROMIS scheme, and he ran publishing companies as intelligence fronts. Robert Maxwell is practically the reason why modern science publishing works the way it does, like a cartel. There's a 7-year-old article in the Guardian about it entitled Is the staggeringly profitable business of scientific publishing bad for science? Go look it up if you doubt this.

Robert Kadlec was involved in both the Dark Winter smallpox tabletop exercise in 2001 and Crimson Contagion in 2019. His whole shtick was fearmongering about terrorists weaponizing viruses so he could funnel more money into biodefense and to his defense contractor buddies like Fuad at BioPort/Emergent BioSolutions. The same year as Dark Winter, 9/11 happened, which is another massive can of worms. In short, the CIA, Mossad, Saudi Intelligence, and compromised elements of the US DOS in league with the Bush/PNAC gang all did 9/11 as a Reichstag Fire-like event to justify going into MENA and killing people, to loot gold from the basement of the Twin Towers, and to cover up financial crimes and embezzlement by destroying SEC and Pentagon records, and not OBL, who by then was a decrepit fossil on dialysis and was replaced by numerous body doubles in subsequent years. Two planes can't make three buildings fall into their own footprints. The "Dancing Israelis" had foreknowledge of the attacks, and even admitted as much on a talk show. Airline stocks were shorted before 9/11 by Israel-based investors, further indicating foreknowledge.

Shortly after 9/11, US-based spooks conducted a second false flag event in the form of Amerithrax, where they sent anthrax-laced envelopes to Tom Daschle and Patrick Leahy and their staff, who opposed our entry into war in the Middle East. At first, Brian Ross with ABC falsely reported that the anthrax came from Saddam's stocks because of the presence of a "bentonite additive", but this would turn out to be Peter Jahrling talking utter bullshit about what he saw under a microscope. The anthrax was later traced to Bruce Edwards Ivins, a scientist at USAMRIID, who conveniently committed suicide with Tylenol before the FBI could finish their investigation.

Throughout the 2000s, the growing "biodefense network" in the US, branching off from USAMRIID and Fort Detrick and into civilian laboratories conducting GOF/DURC research, vastly expanded their facilities and their portfolio, buoyed by all the fearmongering and raw bullshit about terrorists and bioweapons in the early 2000s. Edward Hammond, a concerned scientist, started a watchdog group called the Sunshine Project to study the proliferation of these labs throughout the US. What he found was unauthorized persons were handling Select Agents (those pathogens defined as most suited for weaponization), often in too low of biosafety level labs, sometimes even in university labs not even a football field away from classrooms full of students. When the Sunshine Project tried to FOIA their records, they got back completely redacted, blanked-out sheets of paper. We see the same pattern today, with people trying to FOIA public health agencies about COVID-19 and getting back PDFs that are nothing but over a hundred blank pages.

"We're vewy sowwy, this is a nationaw secwurity matter! You can't has unredacted documents, uwu!"

This all came to a head in a hearing in 2007 led by Bart Stupak, the transcript of which is available under the title Germs, Viruses, and Secrets: The Silent Proliferation of Bio-Laboratories in the United States, where Edward Hammond was lined up opposite the biolab apologist Gigi Gronvall who insisted that these labs were "necessary" to "prevent bioterrorism". That same year, the disgusting spooks conducting offensive depopulation bioweapon research in the guise of "biodefense" decided that rather than allow themselves to be FOIAd by watchdog orgs, they would simply outsource the research.

While the biolabs that Edward Hammond investigated were quietly shuttered, Nathan Wolfe, a close friend and confidant of Jeffrey Epstein, Ghislaine Maxwell, and Boris Nikolic, started the Global Viral Forecasting Institute, which was later renamed simply Global Viral. Nathan Wolfe was one of the founding members of Ghislaine Maxwell's fake ocean charity, TerraMar, which you can easily verify by going on the Wayback Machine and looking at TerraMar's website, which showcases Nathan Wolfe's mug in the lineup of their "founding citizens". TerraMar was supposedly an ocean conservation initiative (see my comments about environmentalism, above), but the real purpose of it was to allow Ghislaine and her fellow uber-wealthy human traffickers to engage in seasteading to avoid continental laws against various things, like moving contraband and viciously raping small children.

Boris Nikolic is buddies with Bill Gates and was involved in the Particles for Humanity program to track and trace vaccinated people in third-world shitholes. The Gates Foundation are also heavily involved with GAVI and CEPI, which are basically just vehicles for Bill Gates to stick needles in whoever he wants.

Nathan Wolfe was on DARPA's Defense Science Research Council, he was on the editorial board of EcoHealth Alliance, and he's a World Economic Forum "Technology Pioneer". He cited Jeffrey Epstein and Boris Nikolic in the acknowledgments to his book, The Viral Storm: The Dawn of a New Pandemic Age. He was also a major consultant on the movie Contagion. Nathan Wolfe can be seen on video hobnobbing around in Africa with Karen Saylors, the head of Labyrinth Global Health.

EcoHealth Alliance, the NGO implicated in the leaked DEFUSE docs, was originally founded as the Wildlife Preservation Trust by Margaret Rockefeller and Gerald Durrell. Later, it was renamed EcoHealth Alliance, and Peter Daszak, the son of a Ukrainian fucking Stepan Bandera sympathizer and an anti-human eco-nutjob obsessed with preventing the sale of wild animals in China, became its president.

Nathan Wolfe is a CIA and Mossad asset. Peter Daszak is a CIA asset; Andrew Huff, the former VP of EcoHealth, told us as much, and gave us the In-Q-Tel pitch decks to prove it. Karen Saylors is also an intelligence asset. Basically, all of these "virus-hunting NGOs" are spook fronts, the sole purpose of which is to funnel cash from DARPA, DTRA, In-Q-Tel, and USAID into foreign biolabs to buy viruses for rich Rockefeller scumfuck murderers to kill the world's excess population with.

Nicole Junkermann, another Mossad asset, conspired with "Midazolam" Matt Hancock to steal the NHS records of UK citizens. This was documented extensively by Johnny Vedmore.

EcoHealth Alliance and Metabiota were involved in something called the Global Virome Project, led by Dennis Carroll at USAID, another fucking spook, who ought to have been dragged before Congress and questioned vigorously. EcoHealth Alliance was also involved in a program by UC Davis and USAID called EPT-PREDICT.

Nathan Wolfe's company, Metabiota, was involved in bungling the Ebola response in West Africa. They were also heavily involved in disbursing DOD funds to Ukrainian biolabs. Hunter Biden's investment firm, Rosemont Seneca, was a major investor in Metabiota.

In 2005, Katalin Kariko published a paper in Cell journal about using pseudouridylated mRNA (or modRNA) so that mRNA-based therapeutics could evade detection by toll-like receptors. Her work led to the founding of Moderna and BioNTech. Colonel Dan Wattendorf, another psychotic with a god complex, was involved in DARPA shilling for Moderna to the tune of millions of dollars to research mRNA-based monoclonal antibody therapies for Chikungunya virus under the ADEPT: PROTECT program back in 2013. Dan Wattendorf then went on to work for the Gates Foundation.

One of the cofounders of Moderna was Robert Langer, a close associate of Charles Lieber, who, in turn, was indicted by the DOJ for taking money under the table from China, against the terms of his military grants. Charles Lieber is a bionanotech expert at Harvard who specializes in things like blending semiconductor nanowires with human brain tissue to make BCIs and mind control devices. He had funding from DARPA, ONR, AFOSR, NIH, and MITRE.

If you look up the Internet of Bodies, Ian Akyildiz, Josep Jornet, Charles Lieber, and their papers and files, it immediately becomes clear that the same strain of technocracy outlined by Zbigniew Brzezinski (and criticized by Patrick Wood) plans to turn most of humanity into docile and controllable cyborg slaves, because our liberties clearly offend the ruling class so much. DARPA's Brain Initiative started under the Obama admin is heavily involved with this sort of thing, and Battelle and Rice have working prototypes of the tech, which involves slipping semiconductor nanoparticles into brain tissue so you can beam wireless energy into them to open ion channels in people's neurons, kind of like having a wireless electrode in someone's head made out of smart dust. It has been tested on flies, and, in principle, it works, but a lot of the underlying tech is still theoretical. With AI and synthetic biology advancing as fast as they are, it won't be theoretical for very long. The reason why the Overclass want this tech is so they can reach inside people's brains and fuck with their reward networks so they will be satisfied with eating bugs and living in pods. Think wireheads from Ringworld.

In 2010/2011, a brilliant scientist at MIT named Todd Rider developed a universal antivirus named DRACO, with biodefense grant money from DARPA and DTRA. DRACO is a protein biologic drug that keeps virally infected cells from reproducing by activating apoptosis in those cells if it encounters dsRNA. It is highly specific to infected cells and leaves healthy cells unharmed, providing a whole week of protection against pretty much any arbitrary virus. It also works on viruses with DNA genomes, because they also produce dsRNA as part of their replication process.

He wanted to continue his work on DRACO at Draper Lab, but when Ken Gabriel took over at Draper, he canceled Todd Rider's grants. Ken Gabriel is the lap dog of Regina Dugan, who was formerly the head of DARPA, and who is obsessed with microchipping humans and making things like "ID pills you can swallow". Regina Dugan, after conducting secret projects for Motorola and Google's ATAP (it's all transhumanism bullshit about chipping and tracking people, go look it up) is now the head of Wellcome Leap, the transhumanist arm of the Wellcome Trust, which was formerly led by Jeremy Farrar, who was involved in the COVID-19 coverup but is now Chief Scientist of the WHO. Go figure. Ken Gabriel was, until recently, Wellcome Leap's COO. So, the guy who canceled a grant for a universal antivirus that was proven to work then went on to work for a think tank connected to COVID cover-uppers. Right.

Moderna's CEO, Stephane Bancel, was formerly the CEO of bioMerieux. Alain Merieux and the French government helped China build the high-containment lab at the Wuhan Institute of Virology. You can see Alain Merieux and Klaus Schwab being given the CCP's Reform Friendship Award on stage, side-by-side. Chairman Mao, Hu Jintao, and Xi Jinping were, and are, all literally Illuminati assets and Communist China is an Illuminati project to build a working prototype of the one-child policy, social credit score, CCTV-camera-inundated open-air prison that the technocrats plan to implement literally everywhere. This idea that people have that China is this separate "Red Menace" from our power structures is illusory. Chairman Mao was initiated by Yale-in-China and the Skull and Bones just like the fucking Bushes. It's all kayfabe. There is no foreign adversary. If you are sent to war against China in the Taiwan Strait, you will literally be ordered by the Illuminati to kill other peasants controlled by... *drumroll*... the Illuminati. All of these world leaders are in cahoots and fully initiated Illuminati behind closed doors. They just put on a fake show for gullible morons to lap up. Do not get drafted for World War III, whatever you do. It is a depopulation scam conducted by profoundly sick, power-drunk, child-fucking bastards.

In 2010, the Rockefeller Foundation published a document entitled Scenarios for the Future of Technology and International Development. It contained a scenario entitled "Lock Step", about the adoption of mass surveillance technologies and tighter control of people's movements due to a flu pandemic. To quote the article:

At first, the notion of a more controlled world gained wide acceptance and approval. Citizens willingly gave up some of their sovereignty —and their privacy —to more paternalistic states in exchange for greater safety and stability. Citizens were more tolerant, and even eager, for top-down direction and oversight, and national leaders had more latitude to impose order in the ways they saw fit. In developed countries, this heightened oversight took many forms: biometric IDs for all citizens, for example, and tighter regulation of key industries whose stability was deemed vital to national interests. In many developed countries, enforced cooperation with a suite of new regulations and agreements slowly but steadily restored both order and, importantly, economic growth.

Sound familiar?

What about the Johns Hopkins Center for Health Security and their 2017 scenario, The SPARS Pandemic 2025 - 2028?

Here's a quotation from that:

While the FDA, CDC, and other agencies were busy researching possible connections between Corovax and the reported neurological side effects, their efforts were continually undermined by epidemiological analyses produced by various non-governmental individuals and groups. A popular science blogger EpiGirl, for example, began posting interactive maps of the incidence of Corovax side effects in April 2027. To create the maps, EpiGirl collected anecdotes of adverse Corovax side effects using Facebook, Twitter and YouTube and combined them with data downloaded from the HHS Vaccine Adverse Event Reporting System (VAERS), a national vaccine safety surveillance program maintained by the CDC and FDA. EpiGirl also encouraged those among her subscribers who were Apple product users to share health data with her via Apple's ResearchKit and HealthKit applications. EpiGirl's maps were consequently shared widely in social media circles and even included in local and national news reports. The federal government became concerned about the validity of EpiGirl's anecdotal data and the widespread sharing of patient information via the internet.

EpiGirl's data showed a significantly higher incidence rate of nearly every reported side effect; however, federal officials believed that this was largely due to duplicate entries resulting from compiling data from multiple sources. Additionally, EpiGirl's data did not seek to address the cause of the reported side effects, only the incidence rate. Publication of similar results from organizations such as Patients-Like-Me, a group closely associated with the natural medicine movement, further legitimized these independent reports. The government attempted to respond to these claims through formal press releases, but these were neither as visually appealing nor as interactive as EpiGirl's maps and were, therefore, largely ignored. While the federal government appeared to have appropriately addressed concerns around the acute side effects of Corovax, the long-term, chronic effects of the vaccine were still largely unknown. Nearing the end of 2027, reports of new neurological symptoms began to emerge. After showing no adverse side effects for nearly a year, several vaccine recipients slowly began to experience symptoms such as blurry vision, headaches, and numbness in their extremities. Due to the small number of these cases, the significance of their association with Corovax was never determined. As of this writing in 2030, longitudinal studies initiated by the NIH at the beginning of the vaccination program have not reached the next round of data collection, so formal analysis on these symptoms has not yet been conducted. Furthermore, these cases arose from the initial cohort of vaccine recipients—those in high risk populations, including those with other underlying health conditions—making it increasingly difficult to determine the extent to which these symptoms are associated with vaccination.

Does that sound familiar? Again, this was published in 2017.

"OMG, science bloggers tracking vaccine side effects! OMG, it really does cause neurological disorders!"

Interesting how the COVID-19 vaccines cause encephalitis, seizures, Guillain-Barre and other neurological issues. Just like the "Corovax" from the scenario.

When the COVID-19 outbreak occurred in Wuhan in 2019, it was shortly after Jeffrey Epstein's murder in prison, as well as various anomalies in the overnight repo market indicative of another 2008-style debt bubble pop which were not reported on by the press. COVID-19 covered up the financial meltdown by justifying massive lockdowns which allowed for a wealth transfer from the middle class to the obscenely rich to the tune of trillions of dollars, the embezzlement of hundreds of billions of dollars in COVID aid money, and gave the Fed an excuse to run the money printers in overdrive. The closures of small businesses often became permanent, which only helped the giant monopoly big box stores and e-commerce giants that were allowed to stay open. The unscientific lockdowns were the brainchild of Neil Ferguson at Imperial College London, who ran pandemic simulations based on shitcode that produced apocalyptic estimates of death from COVID-19 if nothing was done to contain it. Neil Ferguson also skipped the quarantine to have an affair with a married woman while everyone else was being told to wear masks and only have sex in glory holes, so obviously, he didn't really give a shit about the virus.

Tedros Adhanom carried water for China and the Deep State by hesitating to declare a pandemic, and then claiming that COVID-19 was droplet-borne when it was an aerosolized, airborne virus. Businesses invested in plexiglass barriers and people wore masks and disinfected surfaces for absolutely fucking nothing.

COVID-19 is very similar to SARS and causes a very similar syndrome characterized by endothelial attack, sepsis, and thromboinflammation, with pulmonary edema and pneumonia as a secondary consequence of this. SARS-CoV-2 is neurotropic, attacks the brain by the transcribial route (through the olfactory nerve), and can cause long-term impairment to several brain structures, particularly the parahippocampal gyrus (which is proximate to the olfactory nerve and heavily involved in spatial memory). SARS-CoV-2 causes a cascade of oxidative stress and inflammation in the lungs which ends in free iron release, hydroxyl radical formation, and aggressive oxidative injury (as in, ferroptosis) in the lungs.

This is why the official treatments of "Tylenol for outpatients, ventilators and steroids for inpatients" were counterproductive and actually ended up killing people more often than not. Tylenol depletes glutathione, the body's master antioxidant. Just ask Bruce Ivins, who took an overdose of it and had his liver implode. Oh wait, you can't, he's dead.

Ventilators with high PEEP settings on compliant lungs also cause massive oxidative stress and VILI, which should be contraindicated in a disease that causes ferroptosis in lung tissue, but wasn't. If you take deoxygenated tissue and hit it with tons of oxygen, it metabolizes hypoxanthine and spews superoxide radicals, which can partake in the Fenton Reaction to make hydroxyl radicals in the presence of free iron ions that aren't caged by ferritin. It's a Catch-22, because a cell producing tons of hypoxanthine (a breakdown product of ATP that increases when there is insufficient oxygen) is already deoxygenated and dying. Look up IRI. Ischemia-Reperfusion Injury. It's the same mechanism of injury.

Bing Liu, a Chinese scientist at the University of Pittsburgh School of Medicine and expert in redox biology and ferroptosis, knew all about this. That's why he was killed.

SARS-CoV-2 Spike can wedge open the Blood-Brain Barrier by affecting rhoA. The virus's proteins interfere with endothelial barrier integrity and promote generalized edema and inflammation. Since the vascular endothelium is basically everywhere in the body, COVID-19 causes a wide variety of symptoms and sometimes appears as an "everything-virus" that can cause anything from gastrointestinal illness to purple toes.

The COVID-19 vaccines pushed on us by the DOD and their defense contractor buddies, obtained through an OTA as "military prototypes to test mass production" and falsely authorized by the FDA as pharmaceuticals, are extremely toxic by multiple mechanisms. The synthetic lipids used to carry the genetic information into people's cells are toxic and inflammatory. According to the research of Kevin McKernan, they are contaminated with plasmid DNA containing the SV40 promoter sequence. Foreign DNA can cause cancer by triggering the cGAS-STING pathway and overwhelming immune surveillance. SARS-CoV-2 Spike is also a toxic and amyloidogenic protein that doesn't belong in the human body, from any source, regardless of whether that's the virus or a vaccine. @Vyor, if you think, "Oh, there's no way it can end up in the bloodstream", then what do you think happens when cells producing this protein are inevitably lysed and burst like pinatas?

Pfizer fucking falsified their Western Blots. They know about the contamination, and they don't fucking care.

I am very certain that the COVID-19 vaccines that people are still being dosed with will cause autoimmunity, infertility, cancer, and neurodegenerative disease.

J. Bart Classen published a paper entitled COVID-19 and Illegal US Bioweapons Activity, an Insider's Revelations, where he claimed that the Mossad and Zami Ben-Sasson were involved in developing prion-based bioweapons for depopulating the planet. Katherine Watt and Sasha Latypova outlined how mass murder with vaccines has effectively been legalized through the PREP act and multiple layers of immunity from liability, all of which were cleverly crafted to allow for depopulation agents to be deployed en masse with no legal recourse for the people being murdered.

And, at the eleventh hour, it has come out in hearings that Anthony Fauci not only perjured himself in his testimony about GOF research, but that NIH scientists illegally evaded FOIA requests by using private email addresses and substituting letters in people's names with symbols.

I'm not going to mince words. None of this was a fucking accident. It wasn't a racoon dog in a wet market. It wasn't a lab accident. That's bullshit. These megalomaniacs are trying to kill and corral us on purpose and turn the entire planet into one big open-air prison where they control the demography through insane biopolitical and eugenics schemes.

It's not just Anthony Fauci. It's not just Ralph Baric. It's an entire rat's nest of disgusting Deep State spooks.

Hundreds, possibly even thousands of evil cocksuckers belong UNDER THE JAIL for all of this. The problem is that the people responsible also own the fucking jails.

 

[Vyor]

Ocean Acidification (and associated Coral Reef loss, with cascading effects on fish stocks)

You were doing so well until you said this.

Do you know what causes Ocean Acidification? Atmospheric CO2.

 

[Iconoclast]

You were doing so well until you said this.

Do you know what causes Ocean Acidification? Atmospheric CO2.

That is not the exclusive source. It is also caused by SO2. I know this because I work on, and start, and turn a wrench on, giant marine diesel engines the size of your living room.

 

[Vyor]

That is not the exclusive source. It is also caused by SO2. I know this because I work on, and start, and turn a wrench on, giant marine diesel engines the size of your living room.

NO2 is also a problem, yes.

The first is rarely talked about because it's rare outside of China and you constantly hear about NO2 because it has the source in... artificial fertilizers, which the greens and the media both don't like.

I do comp sci, I understand data analytics, I can watch and observe this shit and can see where you are leaving things out.

 

[Scottty]

NO2 is also a problem, yes.

The first is rarely talked about because it's rare outside of China and you constantly hear about NO2 because it has the source in... artificial fertilizers, which the greens and the media both don't like.

I do comp sci, I understand data analytics, I can watch and observe this shit and can see where you are leaving things out.

How does the stuff you are complaining of him leaving out relate to his main thesis?

 

[Vyor]

How does the stuff you are complaining of him leaving out relate to his main thesis?

If one leaves out, excludes, or lies about basic facts then the conclusion must be wrong. Bad input leads to bad output.

 

[Typhonis]

What it boils down too is that Joe Average is the carbon they want to remove and institute a totalitarian dictatorship that would make Joseph Stalin blush in envy of all on the back of a central bank digital currency using a social credit score and drugs to keep people in line.

The fucking mark of the Beast.

 

[Bacle]

You were doing so well until you said this.

Do you know what causes Ocean Acidification? Atmospheric CO2.

No, this is wrong, ocean acidification is partly the result of over use of fertilizers on land, with the excess nitrogen causing massive algal blooms and de-oxygenated dead zones. SO2 is partly at play in ocean acidifaction as well, and makes the dead zones even worse while increasing overall ocean pH.

Excess CO2 really doesn't do much of anything but increase plant productivity.

 

[Vyor]

No, this is wrong, ocean acidification is partly the result of over use of fertilizers on land, with the excess nitrogen causing massive algal blooms and de-oxygenated dead zones. SO2 is partly at play in ocean acidifaction as well, and makes the dead zones even worse while increasing overall ocean pH.

Excess CO2 really doesn't do much of anything but increase plant productivity.

CO2 dissolves into the ocean, it's one of the biggest sinks of it.

 

[Vyor]

What it boils down too is that Joe Average is the carbon they want to remove and institute a totalitarian dictatorship that would make Joseph Stalin blush in envy of all on the back of a central bank digital currency using a social credit score and drugs to keep people in line.

The fucking mark of the Beast.

take your meds.

 

[Bacle]

CO2 dissolves into the ocean, it's one of the biggest sinks of it.

Yes, and diatoms use it to make their shells, as well as other animals.

It's when other shit makes the ocean too acidic, like SO2 and excess fertilizer caused dead zones, then diatoms cannot process CO2 correctly for shell construction.

CO2 isn't the problem, it's the shit that interrupts the usual CO2 cycle that causes problems, and a lot of time that is excess SO2, excess fertilizer caused algal blooms, and industrial waste dumping.

 

[Vyor]

Yes, and diatoms use it to make their shells, as well as other animals.

It's when other shit makes the ocean too acidic, like SO2 and excess fertilizer caused dead zones, then diatoms cannot process CO2 correctly for shell construction.

CO2 isn't the problem, it's the shit that interrupts the usual CO2 cycle that causes problems, and a lot of time that is excess SO2, excess fertilizer caused algal blooms, and industrial waste dumping.

Yes, and governments keep hammering on both of those. They don't like coal power for a reason and they hate farmers for the same reason.

 

[Bacle]

Yes, and governments keep hammering on both of those. They don't like coal power for a reason and they hate farmers for the same reason.

The fertilizer issue can be solved without hurting farmers, and is more an issue of many types of intensive ag practices doing away with natural nitrogen fixing plants in the mix, in favor of mono-crops.

Mono-cropping is the real problem, a proper mix of plants in the same field can yield several different crops while not needing to dump tons of industrially sourced fertilizer on it, which doesn't stay in the soil and washes out/down stream rather seriously.

Shit, just planting massive amounts of white clover in ag fields would massively reduce fertilizer requirements, and other nitrogen fixing plants can be used to reduce the amount of excess nitrogen washing into the ocean, which contributes to the acidification problems.

Edit: White clover is also very good for bees, so would help pollinator populations as well, which nitrogen fertilizers don't.

 

[Vyor]

The fertilizer issue can be solved without hurting farmers, and is more an issue of many types of intensive ag practices doing away with natural nitrogen fixing plants in the mix, in favor of mono-crops.

Mono-cropping is the real problem, a proper mix of plants in the same field can yield several different crops while not needing to dump tons of industrially sourced fertilizer on it, which doesn't stay in the soil and washes out/down stream rather seriously.

Shit, just planting massive amounts of white clover in ag fields would massively reduce fertilizer requirements, and other nitrogen fixing plants can be used to reduce the amount of excess nitrogen washing into the ocean, which contributes to the acidification problems.

Edit: White clover is also very good for bees, so would help pollinator populations as well, which nitrogen fertilizers don't.

I very much agree that there are much better solutions than just attacking farmers, but saying that the media and such never talk about the problems from excess fertilizer is patently absurd and it's what iconoclast claimed.

When you start from the wrong position, you always end up at the wrong end state. Basic data science.

 

[Doomsought]

The fertilizer problem can easily by using rice fields as settlement ponds. The slow flow of water through the fields allows the fertilizer to settle, and the rice absorbs the fertilizer.

 

[Iconoclast]

NO2 is also a problem, yes.

The first is rarely talked about because it's rare outside of China and you constantly hear about NO2 because it has the source in... artificial fertilizers, which the greens and the media both don't like.

I do comp sci, I understand data analytics, I can watch and observe this shit and can see where you are leaving things out.

You're right. I did leave things out. Because I didn't think anyone would be interested in all the sordid little details. Do you know who's leaving out even more? The media and all those precious institutions you take for granted. They've left out the immense potential for harm that these "vaccines" (actually, literally BTWC proscribed toxins masquerading as vaccines) are capable of.

I'm going to lay out, in no uncertain terms, why the COVID-19 vaccine is so lethal. @posh-goofiness will probably love this.

First off, transfecting cells with foreign nucleic acids is a gene therapy technique. If you want to genetically transform a cell, you have to get a nucleic acid past its membrane and inside it. There are various ways of doing this. One is to enclose that nucleic acid inside a lipid micelle and fuse it with the cell, depositing its cargo inside. Another way is by tagging it with a cell-penetrating peptide, like HIV TAT. You can also use a viral vector, like a replication-defective virus, to insert foreign genetic material into a cell. Other methods include things like making membranes permeable to allow stuff in, like electroporation.

DNA makes RNA which makes proteins. This is how it always works. When your cells need a protein, the nucleus first copies DNA to RNA, and then the RNA leaves the nucleus and encounters ribosomes that read it and turn it into a protein.

The general belief is that this is a one-way process and that RNA cannot become DNA, but this is technically false. Reverse transcription can make DNA from RNA. It's how HIV integrates into the genome as a provirus; it has a reverse transcriptase, hence it's a retrovirus. Cells also have endogenous reverse transcriptases, like LINE-1 RTs, which can pick up RNA and integrate it into the genome.

Normally, when you want to make a protein biologic drug, like recombinant insulin or Hep B subunit vaccines, you need a bioreactor. This is just a big steel vat with bacteria or yeast in it. You can use all sorts of things; E. coli, brewer's yeast, spirulina, whatever.

So, you've taken this bacteria, or yeast, or cyanobacteria, or whatever, and you've transfected it with foreign nucleic acids, usually plasmid DNA, and then you've cultured the cells, right? Now, you can lyse the cells, centrifuge them, pass them through column chromatography, and collect your protein.

With an mRNA or DNA vaccine, you are the bioreactor. Instead of E. coli or yeast making proteins, it's you. It's your cells.

The whole point of the mRNA platform is to get away from things like culturing flu vaccines in chicken eggs, or making subunit vaccines in bioreactors, and move to a reconfigurable vaccine delivery system that can be tweaked for any imaginable antigen. In theory, changing the design of an mRNA vaccine is as simple as swapping the payload with different mRNA encoding a different antigen.

In the case of COVID-19 vaccines, the goal is to produce SARS-CoV-2 Spike as a vaccine antigen. SARS-CoV-2 Spike is what's called a peplomer. It's one of the turkey-leg-shaped proteins that stud the exterior of the virus. This is how Spike actually works:



Spike is composed of S1 and S2 subunits that perform different functions. Generally speaking, Spike enables fusion between the viral membrane and the host cell's membrane by first binding to ACE2, and then being cleaved by TMPRSS2, which allows the stalk of the protein to perform its function, dragging the two membranes together.

The vaccines for COVID-19 are meant to introduce nucleic acids coding for this specific protein into human cells. The Spike sequence has been modified with two prolines (that is, it isn't regular SARS-CoV-2 Spike but a "2P Spike" lab construct). Once the foreign nucleic acid is inside the cell, the cell's own translation machinery make Spike, which migrates to the cell surface and anchors in place with a transmembrane domain. Then, dendritic cells grope around for it and now you have antibodies, or so the story goes.

What could possibly go wrong?

A whole lot of things!

• Synthetic amino lipids like SM-102 combined with polyethylene glycol do not belong in the human body. They're like a synthetic oil. Extremely toxic and inflammatory. They can trigger massive allergic reactions, including full-blown anaphylaxis. Better have an EpiPen handy!
• LNPs are well-known to widely distribute in the human body, including accumulating in the brain and other vital organs, as well as the reproductive organs. They readily bypass the blood-brain barrier. Do you want a delivery mechanism that readily bypasses the BBB to carry instructions into your brain to make Spike? If not, then why not?
• Pseudouridylated mRNA (also known as modRNA or nucleoside-modified messenger RNA) skips teeth in ribosomes. This is also known as +1 frameshifting. As a result, the protein produced by this process is often not even Spike at all, but pure gobbledygook. A +1 frameshift means that all subsequent codon reads will be incorrect and result in the wrong amino acid being stitched to the growing polypeptide chain. It doesn't matter if it +1 shifts back to the original frame eventually. The damage is already done.
• The modRNA in mRNA vaccines may also interfere with TLR signaling, which could affect tumor surveillance by cells. Imagine if Katalin Kariko's Cell paper was wrong, and modRNA behaves like a TLR inhibitor and blocking the TLR signaling cascade instead of merely evading binding and activating TLRs. TLRs are necessary to detect signs of oncogenesis.
• SARS-CoV-2 Spike itself is seriously, hilariously toxic and inflammatory by multiple mechanisms.
• SARS-CoV-2 Spike has a superantigenic region.
• SARS-CoV-2 Spike binds endotoxins with a lipopolysaccharide-binding region. God help you if the vaccine itself was tainted with endotoxins.
• SARS-CoV-2 Spike has a nuclear localization signal and interferes with P53 and BRCA, which also inhibits crucial anticancer functions in cells. Hello, rapid-onset cancer.
• SARS-CoV-2 Spike is amyloidogenic and prionogenic. Yes, this is exactly what it sounds like.
• Having an mRNA or DNA vaccine convince antibodies to bind to otherwise healthy cells is boneheaded on the very face of it, because immune cells will kill those cells without fail.
• The COVID-19 vaccines are causing IgG4 class switching, which causes the body to treat SARS-CoV-2 Spike like a harmless allergen and ignore it.
• The vaccines are now known to be contaminated with plasmid DNA containing the SV40 promoter sequence, which is extremely hazardous. Pfizer knew about this but falsified their western blots and their submissions to regulators.

If you happen to doubt any of this, well, I've got plenty of references to back it up. Also, I might add, it is impossible for the people pushing these vaccines to have failed to recognize any or all of this. Hanlon's Razor does not apply, because you would have to be an absolute drooler to be a PhD involved in vaccine design and not notice any or all of this. The harm is intentional. The vaccine manufacturers' factories are crime scenes.

The vaccines actually, literally ought to be banned from use immediately and everyone involved in their manufacture and distribution ought to be arrested.

Immunogenicity of lipid nanoparticles and its impact on the efficacy of mRNA vaccines and therapeutics - Experimental & Molecular Medicine

Drugs consisting of mRNA encapsulated in lipid nanoparticles (LNP), such as the vaccines developed for COVID-19, are poised to have a massive impact in future therapy, but researchers are still learning about their interactions with the immune system. Hyukjin Lee and colleagues at Ewha Womans...

www.nature.com

There are only three RNA/LNP-based drugs approved by the FDA. Following the 2018 approval of amyloidosis siRNA gene therapy, Onpattro, Moderna (Spikevax) and Pfizer's (Comirnaty) COVID-19 mRNA vaccines were approved in 202112,13,14. More than two billion people were vaccinated with the COVID-19 vaccine at the end of 2021, generating more than $50 billion in sales. Clinical studies for LNP-formulated gene therapies, including mRNA vaccines, are currently taking place, and as pharmaceutical companies continue to invest in RNA/LNP-based medicines, it is anticipated that more pharmaceuticals will be created and licensed15. Since the RNA/LNP platform is still in its early stages, it is unknown how these vaccines impact an individual's body. After inoculation, several side effects of the COVID-19 vaccine have been reported, and many studies have been conducted on the immune function of LNPs16. It appears that the immune function of LNPs exerts contrasting effects. Although it is advantageous when the immune activity of LNPs is positive, there is a possibility that adverse effects could arise as a result of immunological action. Since the immune system is very complex and has various mechanisms, a deeper understanding of the immune system is needed to determine how LNPs affect the body. Moreover, various techniques for controlling LNP effects on the immune system should be established.

mRNA, Nanolipid Particles and PEG: A Triad Never Used in Clinical Vaccines is Going to Be Tested on Hundreds of Millions of People

The WHO warned in December 2019 of the appearance in Wuhan (China) of an outbreak of a highly contagious respiratory lung disease. It was concluded that its origin was due to a new Betacoronavirus that was named as SARS-CoV2...

biomedres.us

Moderna and Pfizer-BioNTech's "pseudo-vaccines" for COVID-19 contain mRNA enveloped by lipid nanoparticles (LNP) and polyethylene glycol (PEG). None of these 3 components have been approved for vaccines or parenteral drugs. Research has shown that LNPs easily enter the brain and can trigger immune reactions, especially after the second dose. More than 70% of the American population is allergic to PEG, so these vaccines can cause allergic reactions and anaphylaxis

There are well-founded suspicions that these vaccines can insert themselves in our DNA, causing mutations whose impact is unknown and that could even be transmitted to our offspring. We explain how the mRNA existing in the cell cytosol can enter the nucleus both during cell division (mitosis and meiosis) and at rest (interphase). In addition, the possible routes of integration of DNA and RNA in our chromosomes through reverse transcripases (RT) are discussed, especially in sperm where a specific endogenous RT has been identified.

https://www.jacionline.org/article/S0091-6749(21)00565-0/fulltext

On December 8, 2020, the world watched as the first dose of coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccine was given in the United Kingdom. The subsequent US Food and Drug Administration emergency use authorization of both Pfizer-BioNTech and Moderna mRNA vaccines was historic, because the use of the mRNA platform had never progressed beyond phase 1 to 2 trials.1 Encouraging preclinical data for the COVID-19 mRNA vaccines and phase 1 to 3 trial data2-8 demonstrating 95% efficacy against COVID-19 had been published. Given the public health emergency and the worldwide death count of nearly 1.8 million, a vaccine to prevent COVID-19 was critically needed.

However, within 24 hours of the first vaccination, media reported that 2 individuals had developed anaphylaxis minutes after administration of the Pfizer-BioNTech COVID-19 vaccine. By December 23, 2020, 1,893,360 first doses of Pfizer-BioNTech COVID-19 vaccine had been administered in the United States and 21 cases of anaphylaxis had been reported.9 One month later, the Centers for Disease Control and Prevention reported that 10 anaphylactic events had occurred out of 4,041,396 first doses of Moderna COVID-19 vaccinations.10 At the time of this writing, the rates of anaphylaxis are calculated at 5.0 cases per million for the Pfizer-BioNTech and 2.8 cases per million for the Moderna vaccine, although a minority of the country has been vaccinated. If the current vaccine reactions remain constant, the rate of anaphylaxis from COVID mRNA vaccines will be 2 to 5 times the rate of other commonly administered vaccines such as Tdap (0.51 per million) and the trivalent inactivated flu vaccine (1.35 per million) (reviewed in McNeil and DeStefano11).

Biomembrane-Derived Nanoparticles in Alzheimer’s Disease Therapy: A Comprehensive Review of Synthetic Lipid Nanoparticles and Natural Cell-Derived Vesicles - PMC

Current therapies for Alzheimer’s disease used in the clinic predominantly focus on reducing symptoms with limited capability to control disease progression; thus, novel drugs are urgently needed. While nanoparticles (liposomes, high-density ...

pmc.ncbi.nlm.nih.gov

Current therapies for Alzheimer's disease used in the clinic predominantly focus on reducing symptoms with limited capability to control disease progression; thus, novel drugs are urgently needed. While nanoparticles (liposomes, high-density lipoprotein-based nanoparticles) constructed with synthetic biomembranes have shown great potential in AD therapy due to their excellent biocompatibility, multifunctionality and ability to penetrate the BBB, nanoparticles derived from natural biomembranes (extracellular vesicles, cell membrane-based nanoparticles) display inherent biocompatibility, stability, homing ability and ability to penetrate the BBB, which may present a safer and more effective treatment for AD. In this paper, we reviewed the synthetic and natural biomembrane-derived nanoparticles that are used in AD therapy. The challenges associated with the clinical translation of biomembrane-derived nanoparticles and future perspectives are also discussed.

Japanese study shows high accumulation of LNP-mRNA from Pfizer vaxxine in mammalian ovaries after injection : Free Download, Borrow, and Streaming : Internet Archive

This study shows high accumulation of LNP-mRNA from Pfizer in mammalian ovaries after injection. Japanese study, allegedly leaked via and information request...

archive.org

This study shows high accumulation of LNP-mRNA from Pfizer in mammalian ovaries after injection. Japanese study, allegedly leaked via and information request from Dr. Bridle and colleagues.

N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting - Nature

A study demonstrates that nucleotide modifications in mRNA-based therapeutics can lead to +1 ribosomal frameshifting during translation, yielding products that can trigger immune responses.

www.nature.com

In vitro-transcribed (IVT) mRNAs are modalities that can combat human disease, exemplified by their use as vaccines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). IVT mRNAs are transfected into target cells, where they are translated into recombinant protein, and the biological activity or immunogenicity of the encoded protein exerts an intended therapeutic effect1,2. Modified ribonucleotides are commonly incorporated into therapeutic IVT mRNAs to decrease their innate immunogenicity3,4,5, but their effects on mRNA translation fidelity have not been fully explored. Here we demonstrate that incorporation of N1-methylpseudouridine into mRNA results in +1 ribosomal frameshifting in vitro and that cellular immunity in mice and humans to +1 frameshifted products from BNT162b2 vaccine mRNA translation occurs after vaccination. The +1 ribosome frameshifting observed is probably a consequence of N1-methylpseudouridine-induced ribosome stalling during IVT mRNA translation, with frameshifting occurring at ribosome slippery sequences. However, we demonstrate that synonymous targeting of such slippery sequences provides an effective strategy to reduce the production of frameshifted products. Overall, these data increase our understanding of how modified ribonucleotides affect the fidelity of mRNA translation, and although there are no adverse outcomes reported from mistranslation of mRNA-based SARS-CoV-2 vaccines in humans, these data highlight potential off-target effects for future mRNA-based therapeutics and demonstrate the requirement for sequence optimization.

The BNT162b2 mRNA vaccine against SARS-CoV-2 reprograms both adaptive and innate immune responses

The mRNA-based BNT162b2 vaccine from Pfizer/BioNTech was the first registered COVID-19 vaccine and has been shown to be up to 95% effective in preventing SARS-CoV-2 infections. Little is known about the broad effects of the new class of mRNA vaccines, especially whether they have combined...

www.medrxiv.org

The mRNA-based BNT162b2 vaccine from Pfizer/BioNTech was the first registered COVID-19 vaccine and has been shown to be up to 95% effective in preventing SARS-CoV-2 infections. Little is known about the broad effects of the new class of mRNA vaccines, especially whether they have combined effects on innate and adaptive immune responses. Here we confirmed that BNT162b2 vaccination of healthy individuals induced effective humoral and cellular immunity against several SARS-CoV-2 variants. Interestingly, however, the BNT162b2 vaccine also modulated the production of inflammatory cytokines by innate immune cells upon stimulation with both specific (SARS-CoV-2) and non-specific (viral, fungal and bacterial) stimuli. The response of innate immune cells to TLR4 and TLR7/8 ligands was lower after BNT162b2 vaccination, while fungi-induced cytokine responses were stronger. In conclusion, the mRNA BNT162b2 vaccine induces complex functional reprogramming of innate immune responses, which should be considered in the development and use of this new class of vaccines.

Impact of the SARS-CoV-2 Spike Protein on the Innate Immune System: A Review - PMC

The Spike protein enables the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by binding to multiple receptors, including the angiotensin-converting enzyme 2 (ACE2). Scientific studies also indicate that Spike is involved in ...

pmc.ncbi.nlm.nih.gov

Notwithstanding, if the molecular basis is still unknown, a direct interaction between the SARS-CoV-2 Spike protein and TLR4 was demonstrated by a surface plasmon resonance assay [67]. TLR4 can also be implicated in the inflammatory process mediated by Spike, including in the central nervous system (CNS), and these data are corroborated by different publications [68-70]. According to Aboudounya and Heads [70], the interaction between Spike and TLR4 leads first to the activation of the canonical pathway, initiated by the myeloid differentiation primary response 88 (MyD88) and resulting in the translocation of the NF-κB factor, and second the activation of the MAPK pathway via the transforming growth factor-β (TGF-β)-activated kinase 1 (TAK1), to produce proinflammatory cytokines and chemokines. The activation of the non-canonical pathway, via the toll/interleukin-1 receptor (TIR)-domain-containing adaptor-inducing beta interferon (TRIF) and TRIF-related adaptor molecule (TRAM) system (TRIF/TRAM system), is also possible. This molecular cascade induces the production of anti-inflammatory cytokines, such as IL-10, and, above all, the production of IFN-I [70].

Thus, both Spike/TLR2 or Spike/TLR4 interactions can be, ipso facto, involved in an inflammatory process via the activation of the NF-κB and MAPK pathways.

https://www.pnas.org/doi/10.1073/pnas.2010722117

Here, we used computational modeling to determine whether SARS-CoV-2 S possesses SAg-like fragments and activity. We demonstrate that a polybasic insert present in SARS-CoV-2 S, which is absent in the S glycoprotein of other SARS-related β-CoVs, mediates high-affinity, nonspecific binding to the TCR. Notably, a motif of ∼20 amino acids enclosing this insert unique to SARS-CoV-2 has sequence and structure features highly similar to those of the toxin SEB. Our analysis further indicates that a rare SARS-CoV-2 S mutation detected in a European strain may potentially enhance TCR binding. Moreover, analysis of a cohort of adult COVID-19 patients reveals that those with severe hyperinflammatory disease exhibit skewing of the TCR repertoire consistent with SAg activity. Therefore, these findings have important implications for the management and treatment of both MIS-C and COVID-19 patients with hyperinflammatory syndrome.

SARS-CoV-2 spike protein binds to bacterial lipopolysaccharide and boosts proinflammatory activity - PMC

There is a link between high lipopolysaccharide (LPS) levels in the blood and the metabolic syndrome, and metabolic syndrome predisposes patients to severe COVID-19. Here, we define an interaction between SARS-CoV-2 spike (S) protein and LPS, ...

pmc.ncbi.nlm.nih.gov

There is a link between high lipopolysaccharide (LPS) levels in the blood and the metabolic syndrome, and metabolic syndrome predisposes patients to severe COVID-19. Here, we define an interaction between SARS-CoV-2 spike (S) protein and LPS, leading to aggravated inflammation in vitro and in vivo. Native gel electrophoresis demonstrated that SARS-CoV-2 S protein binds to LPS. Microscale thermophoresis yielded a KD of ∼47 nM for the interaction. Computational modeling and all-atom molecular dynamics simulations further substantiated the experimental results, identifying a main LPS-binding site in SARS-CoV-2 S protein. S protein, when combined with low levels of LPS, boosted nuclear factor-kappa B (NF-κB) activation in monocytic THP-1 cells and cytokine responses in human blood and peripheral blood mononuclear cells, respectively. The in vitro inflammatory response was further validated by employing NF-κB reporter mice and in vivo bioimaging. Dynamic light scattering, transmission electron microscopy, and LPS-FITC analyses demonstrated that S protein modulated the aggregation state of LPS, providing a molecular explanation for the observed boosting effect. Taken together, our results provide an interesting molecular link between excessive inflammation during infection with SARS-CoV-2 and comorbidities involving increased levels of bacterial endotoxins.

Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes severe pathophysiology in vulnerable older populations and appears to be highly pathogenic and more transmissible than SARS-CoV or MERS-CoV [[1][1], [2][2]]. The spike (S) protein appears to be a major pathogenic factor that...

www.biorxiv.org

One of the novel sequence insertions resides at the S1/S2 boundary of Spike (S) protein and constitutes a functional nuclear localization signal (NLS) motif "PRRARSV", which may supersede the importance of previously proposed polybasic furin cleavage site "RRAR". Indeed, S protein's NLS-driven nuclear translocation and its possible role in S mRNA's nuclear translocation reveal a novel pathogenic feature of SARS-CoV-2.

SARS-CoV-2 Vaccination and the Multi-Hit Hypothesis of Oncogenesis - PMC

Cancer is a complex and dynamic disease. The “hallmarks of cancer” were proposed by Hanahan and Weinberg (2000) as a group of biological competencies that human cells attain as they progress from normalcy to neoplastic transformation. These ...

pmc.ncbi.nlm.nih.gov

Using bioinformatics (in silico) analyses, Singh and Bharara [190] proved that the S2 subunit of SARS-CoV-2 strongly interacts with well-known tumor suppressor proteins p53 and BRCA1/2, which are frequently mutated in human cancers. These proteins provide a major barrier to neoplastic transformation and tumor progression by their unique ability to act as extremely sensitive collectors of stress inputs and to coordinate a complex framework of diverse effector pathways and processes that protect cellular homeostasis and genome integrity. p53 and BRCA1/2 act predominantly in the cell nucleus regulating cell cycle progression, DNA damage repair and recombination, and gene transcription [191-193]. However, these proteins also play critical roles in the cytoplasm, triggering apoptosis and inhibiting autophagy, thereby contributing to their mission as tumor suppressors [194,195]. Wild-type p53 has been reported to be abnormally sequestered in the cytoplasm of a subset of primary human tumors [196]. A myriad of cancer-associated mutations that disrupt the nuclear targeting of BRCA1 restrict the protein to the cytosol and diminish its nuclear function in homologous recombination repair of DNA breaks [197]. Notably, BRCA1 cytosolic accumulation promotes breast cancer metastasis [198] and independently predicts survival, tumor grade, and recurrence in low-grade basal-like sporadic breast cancers [199].

https://www.sciencedirect.com/science/article/pii/S0006291X2100499X?via%3Dihub

The post-infection of COVID-19 includes a myriad of neurologic symptoms including neurodegeneration. Protein aggregation in brain can be considered as one of the important reasons behind the neurodegeneration. SARS-CoV-2 Spike S1 protein receptor binding domain (SARS-CoV-2 S1 RBD) binds to heparin and heparin binding proteins. Moreover, heparin binding accelerates the aggregation of the pathological amyloid proteins present in the brain. In this paper, we have shown that the SARS-CoV-2 S1 RBD binds to a number of aggregation-prone, heparin binding proteins including Aβ, α-synuclein, tau, prion, and TDP-43 RRM. These interactions suggests that the heparin-binding site on the S1 protein might assist the binding of amyloid proteins to the viral surface and thus could initiate aggregation of these proteins and finally leads to neurodegeneration in brain. The results will help us to prevent future outcomes of neurodegeneration by targeting this binding and aggregation process.

https://pubs.acs.org/doi/10.1021/jacs.2c03925

Seven amyloidogenic sequences distributed over the entire S-protein were identified and named according to the starting position in the S-protein (Figure S2, Supporting Information). All but one (Spike365) of the predicted sequences are in β-sheet conformation in the SARS-CoV-2 Spike cryo-EM structure in its closed state. (1) The C-terminal part of the protein (Spike1166) is not resolved in the structure.

Solubilized peptides (0.1 mg/mL, PBS pH 7.5, 10% HFIP) were monitored for in vitro amyloid fibril formation kinetics using ThT, Congo red birefringence (CR), and negative stain transmission electron microscopy (TEM).

Fibrils from most of the synthetic peptides were detected within a few hours by at least one assay (Table 1, Figure 1). Spike192, Spike601, and Spike1166 fulfilled all our amyloid criteria: sigmoidal ThT kinetics, Congophilicity, and fibrillar ultrastructure (Figure 1, Table 1). Spike192 formed exceptionally well-ordered fibrils comparable to a mix of all peptides (Figures 1C and S3C).

SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19 - PMC

Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by unprecedented clinical pathologies. One of the most important pathologies, is hypercoagulation and ...

pmc.ncbi.nlm.nih.gov

Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by unprecedented clinical pathologies. One of the most important pathologies, is hypercoagulation and microclots in the lungs of patients. Here we study the effect of isolated SARS-CoV-2 spike protein S1 subunit as potential inflammagen sui generis. Using scanning electron and fluorescence microscopy as well as mass spectrometry, we investigate the potential of this inflammagen to interact with platelets and fibrin(ogen) directly to cause blood hypercoagulation. Using platelet-poor plasma (PPP), we show that spike protein may interfere with blood flow. Mass spectrometry also showed that when spike protein S1 is added to healthy PPP, it results in structural changes to β and γ fibrin(ogen), complement 3, and prothrombin. These proteins were substantially resistant to trypsinization, in the presence of spike protein S1. Here we suggest that, in part, the presence of spike protein in circulation may contribute to the hypercoagulation in COVID-19 positive patients and may cause substantial impairment of fibrinolysis. Such lytic impairment may result in the persistent large microclots we have noted here and previously in plasma samples of COVID-19 patients. This observation may have important clinical relevance in the treatment of hypercoagulability in COVID-19 patients.

https://onlinelibrary.wiley.com/doi/10.1111/sji.13160

In conclusion, it is essential to underline that every human cell that intakes the LNPs and translates the viral protein (in case of the mRNA vaccines), or that gets infected by the adenovirus and expresses and translates the viral protein (in case of the adenovirus-based vaccines), is inevitably recognized as a threat by the immune system and killed (Figure 1). There are no exceptions to this mechanism. The severity of the resulting damage and the consequences for health depend on the quantity of the cells involved, on the type of tissue and on the strength of the following autoimmune reaction. For instance, if the mRNA contained in the LNPs would get internalized by cardiac myocytes, and such cells would produce the spike protein, the resulting inflammation would likely lead to the necrosis of the myocardium, with an extent proportional to the number of involved cells. Therefore, it is fundamental to perform pharmacokinetic evaluations in humans, in order to determine the exact biodistribution of the vaccines against COVID-19, and thus to identify the possible tissues at threat.

IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein - PMC

Less than a year after the global emergence of the coronavirus SARS-CoV-2, a novel vaccine platform based on mRNA technology was introduced to the market. Globally, around 13.38 billion COVID-19 vaccine doses of diverse platforms have been ...

pmc.ncbi.nlm.nih.gov

Less than a year after the global emergence of the coronavirus SARS-CoV-2, a novel vaccine platform based on mRNA technology was introduced to the market. Globally, around 13.38 billion COVID-19 vaccine doses of diverse platforms have been administered. To date, 72.3% of the total population has been injected at least once with a COVID-19 vaccine. As the immunity provided by these vaccines rapidly wanes, their ability to prevent hospitalization and severe disease in individuals with comorbidities has recently been questioned, and increasing evidence has shown that, as with many other vaccines, they do not produce sterilizing immunity, allowing people to suffer frequent re-infections. Additionally, recent investigations have found abnormally high levels of IgG4 in people who were administered two or more injections of the mRNA vaccines. HIV, Malaria, and Pertussis vaccines have also been reported to induce higher-than-normal IgG4 synthesis. Overall, there are three critical factors determining the class switch to IgG4 antibodies: excessive antigen concentration, repeated vaccination, and the type of vaccine used. It has been suggested that an increase in IgG4 levels could have a protecting role by preventing immune over-activation, similar to that occurring during successful allergen-specific immunotherapy by inhibiting IgE-induced effects. However, emerging evidence suggests that the reported increase in IgG4 levels detected after repeated vaccination with the mRNA vaccines may not be a protective mechanism; rather, it constitutes an immune tolerance mechanism to the spike protein that could promote unopposed SARS-CoV2 infection and replication by suppressing natural antiviral responses. Increased IgG4 synthesis due to repeated mRNA vaccination with high antigen concentrations may also cause autoimmune diseases, and promote cancer growth and autoimmune myocarditis in susceptible individuals.

OSF

These data conclude that all Pfizer vectors contain a homoplastic 2 copy 72bp SV40 Enhancer associated with more robust expression and nuclear localization. The initial heteroplastic indel was an artifact of the Megahit assembler and short insert libraries. These vectors contain an SV40 Promoter, SV40 Enhancer, SV40 Origin, and an SV40 polyA signal. They do not contain the entire SV40 virus or the SV40 T-antigen.

 

[Iconoclast]

It just keeps getting worse, too. I mean, people are doing the histopathology examinations of the tissues of the vaccine-injured (and those who died from them), and they're seeing Spike protein everywhere. In the brain, too. Not just the deltoid muscle of the shoulder.

Autopsies Prove Widespread Dissemination of Vaccine Spike Protein Across Various Organs and Tissues

New study amplifies call for routine autopsies in individuals who have died following COVID-19 vaccination, which must include Spike protein staining.

petermcculloughmd.substack.com

Clinical Approach to Post-acute Sequelae After COVID-19 Infection and Vaccination - PMC

The spike protein of SARS-CoV-2 has been found to exhibit pathogenic characteristics and be a possible cause of post-acute sequelae after SARS-CoV-2 infection or COVID-19 vaccination. COVID-19 vaccines utilize a modified, stabilized prefusion spike ...

pmc.ncbi.nlm.nih.gov

https://onlinelibrary.wiley.com/doi/10.1111/pin.13491

 

[mrttao]

NO2 is also a problem, yes.

The first is rarely talked about because it's rare outside of China and you constantly hear about NO2 because it has the source in... artificial fertilizers, which the greens and the media both don't like.

I do comp sci, I understand data analytics, I can watch and observe this shit and can see where you are leaving things out.

Are you fucking trolling right now?
He writes multi page essays with multiple multi hour videos which I don't think a single person here reads and watches fully because it would literally take hours to process a single one of his posts.
And you complain he needs to put in more?

 

[Vyor]

So, you've taken this bacteria, or yeast, or cyanobacteria, or whatever, and you've transfected it with foreign nucleic acids, usually plasmid DNA, and then you've cultured the cells, right?

No, you typically use something like CRISPR for that, which is rather different.

Synthetic amino lipids like SM-102 combined with polyethylene glycol do not belong in the human body. They're like a synthetic oil. Extremely toxic and inflammatory. They can trigger massive allergic reactions, including full-blown anaphylaxis. Better have an EpiPen handy!

If you're allergic, which affected an extremely small number of people, not the claimed 70%.

LNPs are well-known to widely distribute in the human body, including accumulating in the brain and other vital organs, as well as the reproductive organs. They readily bypass the blood-brain barrier. Do you want a delivery mechanism that readily bypasses the BBB to carry instructions into your brain to make Spike? If not, then why not?

mRNA, Nanolipid Particles and PEG: A Triad Never Used in Clinical Vaccines is Going to Be Tested on Hundreds of Millions of People

The WHO warned in December 2019 of the appearance in Wuhan (China) of an outbreak of a highly contagious respiratory lung disease. It was concluded that its origin was due to a new Betacoronavirus that was named as SARS-CoV2...

biomedres.us

This is your citation for this, yes?

Not actually written by real doctors. "María José Martínez-Albarracín" is not a doctor and has never been a doctor. She claims to be, but she isn't one. She's a member of the fraudulent org "Doctors for Truth" that, among other things, claims the corona virus didn't actually exist. The only one I can find any actual credentials for is... a Urologist, Alejandro Sousa. Not exactly an expert on nanoparticle chemistry.

(also known as modRNA

The modRNA

MESSENGER, not MOD.

The modRNA in mRNA vaccines may also interfere with TLR signaling, which could affect tumor surveillance by cells. Imagine if Katalin Kariko's Cell paper was wrong, and modRNA behaves like a TLR inhibitor and blocking the TLR signaling cascade instead of merely evading binding and activating TLRs. TLRs are necessary to detect signs of oncogenesis.

"imagine if"

SARS-CoV-2 Spike binds endotoxins with a lipopolysaccharide-binding region. God help you if the vaccine itself was tainted with endotoxins.

... Ok, one, if the endotoxins were there you're fucked anyway. Two, if the spike binds the endotoxins, that would be a good thing because then the endotoxin is bound with the spike. Like, it would fuck up any cell it then attaches to, but you're not any worse off than you were before.

SARS-CoV-2 Spike is amyloidogenic and prionogenic. Yes, this is exactly what it sounds like.

It is most certainly not prionogenic as it doesn't interact with and fold proteins into either more of itself or into a misfolded prion. The paper you linked to show this doesn't even say it does that, it claims that it can bind to other proteins and cause accumulation of those proteins; which is a very different thing.

Having an mRNA or DNA vaccine convince antibodies to bind to otherwise healthy cells is boneheaded on the very face of it, because immune cells will kill those cells without fail.

Agreed

The COVID-19 vaccines are causing IgG4 class switching, which causes the body to treat SARS-CoV-2 Spike like a harmless allergen and ignore it.

That was specifically found with repeated vaccinations, which is very much a "no shit" type of finding to anyone with a brain.

The vaccines are now known to be contaminated with plasmid DNA containing the SV40 promoter sequence, which is extremely hazardous. Pfizer knew about this but falsified their western blots and their submissions to regulators.

They used SV40 as a base from which to build the vaccine from, SV40 is hazardous but the SV40 promoter sequence by itself is not.

Are you fucking trolling right now?
He writes multi page essays with multiple multi hour videos which I don't think a single person here reads and watches fully because it would literally take hours to process a single one of his posts.
And you complain he needs to put in more?

When he says "no one is talking about this problem" and he leaves out "oh yes people are talking about this problem" yes, yes he does in fact need to put more. Or at least be more precise in his statements.