I made this post on Reddit, so I figured I'd put it here. The idea is why Picard resigned from Starfleet, stating it's not the same Starfleet as he remembers. If the show handles it well (which is....doubtful), such a statement would make good sense considering the realities of the Star Trek universe circa 2399.
I think that the Dominion War had a huge impact on Starfleet and it's goals and priorities. Picard's Starfleet career was mostly during peacetime. There were some skirmishes, but for the most part, it was rather peaceful. Only after he became Captain did the threats of the Borg, and later the Dominion become on the forefront of Starfleet policy. The Dominion War especially had a huge change in Starfleet, and likely the Federation as a whole.
The Federation came out of the Dominion War as victors, but it was a bloody affair. The homeworlds of at least two major Federation species came under Dominion occupation (Betazed and Benzar), along with who knows how many colonies. I don't think the Dominion would carry it it's more violent pacification strategies until after the war (as a reminder, Weyoun's plan for Earth was to eradicate the population to curtail future resistance to Dominion rule), I still expect significant destruction on these planets.
Post-Dominion War, Starfleet will have likely lost many of it's officers that remember the Starfleet dedicated to exploration, be it through the war, or even through retirement and aging out. To replace them, Starfleet now consists of personnel whose careers will be primarily the Dominion War, or cadets and newly enlisted personnel that will have a good chance of coming from planets who suffered from Dominion occupation, and will likely hold more hawkish views on Starfleet's role in the Federation.
With the attack on Mars, a huge number of Starfleet personnel were killed likely including many of Starfleet's more "Picard-esque" captains, and admirals who agreed with Picard's lobbying to help the Romulans. The attack likely gave those in Starfleet who preferred a more militarist attitude, wanting the fleet to defend against threats, rather than lose more resources and personnel on a humanitarian mission.
I'd expect that the Federation as a whole still provided support, including welcoming refugees, paying privately owned vessels to help with the evacuation, etc. but Starfleet refocused it's efforts on military defense, rather than humanitarian aid.
Picard certainly isn't happy with these changes, but to the 30 something year old Benzar Captain, who joined Starfleet after his world suffered Dominion occupation, I would expect a different viewpoint than Picard. I expect that Benzar to prefer keeping his ship in strategic defensive positions in case the Borg pop up or something, rather than risk his home coming under assault. The new generation within Starfleet likely sees the occupation of key Federation worlds as a greater failure of Starfleet principles that should not be repeated.