Terthna
Professional Lurker
Maybe; but so far I'm fairly certain that besides this new Trigun anime, no other in recent memory has been altered from the source material this drastically.True but I think you may see more of it as anime continues to become more main streamed. From the 90's with Suncoast and Adult Swim being the only options to Crunchyroll and anime on every streaming service.
While this has been great for fans not having to get fansubs from random sites it also has lead to anime getting more hollywood influence. While it has not really effected plotlines it has lead to more stuff like not being as true to the source materials or more reimagining like Trigun.