Just to bump this up, a Fallout Anthology run popped up in my recommendations.
A Fallout Anthology run involves playing through Fallout, Fallout 2, Fallout 3, Fallout: New Vegas and Fallout 4.
The video in totality is about two and a quarter hours long and while its not a record breaking speedrun, the main speedrunner, named tomatoangus provides some really fun and off the cuff commentary about the tips and techniques and glitches etc that he takes advantage of while playing through all of these games as well as flexing some impressive Fallout lore knowledge and of course amazing gameplay (and clipping) skills.