Alright, so looking at the timeline...
2022: Robert and Anthony House's parents die in an auto gyro accident, Anthony steals Roberts inheritance and starts running H&H Tools. No signs of real economic troubles in the US yet.
2037: Mister Handy robot model released for commercial sale to great success by General Atomics International, so the economy is good enough that middle class people can afford a robot housekeeper/butler.
2042: Mexico City is hit by an earthquake, the Mister Handy robot sells like crazy in Mexico as they are used to help recover from the disaster, Wilson Atomatoys sees its new Giddyup Buttercup bot become its flagship product, and RobCo Industries is founded. No signs of economic issues yet.
2044: Nuka-Cola is released, obviously sells very well.
2047: RobCo is one of the most profitable corporations on the planet.
2051: The US invades Mexico, citing protecting American oil investments and business interests, and Mexico becoming politically unstable. First signs that things are looking rough economically.
2052: The Resource Wars between Europe and the Middle East start, the UN collapses as an international organization. The US undertakes the last manned mission to the moon.
2053: The New Plague hits, the US closes its borders in the first national quarantine (which presumably would include Mexico)
2054: Limited nuclear exchange in the middle east, possible in Europe, probably not great for global trade and any economy anywhere, but the US has already closed itself off from the majority of the outside world for a year at this point.
2055: HalluciGen Incorporated sells its crowd control gas to the US government, guessing riots and civil unrest were an issue by this point.
2058: Isla Negra Holdings begins to take direct control over Point Lookout, Maryland as the New Plague devastated the region.
2060: Olympic Games are held (why? there is a devastating probably artificial plague fucking over the world and Europe and the Middle East have been burning for half a decade). The war between the European Commonwealth and the Middle East petters out as the oil runs dry and the reason for the fighting ceases to exist. the European Commonwealth collapses soon after, probably not great for the global economy. The European civil war begins.
2062: The US federal government seems unable to stop the New Plague (beginning to get the sense they don't want to stop it)
2065: Nuclear reactor in New York City goes supercritical and has a meltdown, electricity rationing goes into effect in the US, and the development of Power Armor begins.
2066: China and the US begin to become aggressive with each other, diplomatic talks fail, and the US announces all of its oil reserves are for domestic use only, China invades Alaska and declares war on the United States. Canada is forced to allow US troops to move through its territory.
2067: Nuka-Cola machines are on just about every street corner in the US (who has the money to get a soda? why would they want to go outside to get one with a super plague still on-going?)
2069: The US begins exploiting Canadian resources heavily, Canadians begin protesting American military presence in Canada. The US bans the "Patriots Cookbook" and attempts to destroy all known copies (lots of unrest problems in the US I'm guessing)
2070: The first Chryslus Motors fusion-powered cars are developed, noted as being "big and expensive" and they sell out within days. (who the hell was buying them? The people dying of plague?)
2072: Vault 79 is finished, US gold reserves are transferred to it from Fort Knox. Galactic Zone opens at Nuka World (why were people still going to a theme park?), Canadians begin to riot in a widespread manner, a bunch of US soldiers try to steal 20 million dollars worth of gold from Vault 79 and die in the attempt (bad news economically speaking when your soldiers are trying to rob you)
2074: US soldiers invade mainland China, supply line issues quickly cause the front to bog down.
2075: The US-China war rages on, both sides experiencing lots of espionage and sabotage, the US gov has lots of secret weapon tech projects in the works.
2076: RobCo gets even bigger, buying out several major competitors. US Senate debates tapping into the largest known uranium reserve on the planet, located in on the east coast, Senator Sam Blackwell embarrasses Senator Clark by revealing that he has made large investments in Atomic Mining Services. Canada is annexed by the US.
2077: Bombs fall, and everyone dies, except the Ghouls I guess.
In conclusion, I can't really tell what the economic situation was. It seems like the people who were already rich in the 2050s and 2060s stayed rich in the 2070s, and everyone else was dying from bioweapons or rioting.