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Especially given the vast number of star systems with no habitable planets and the endless reaches of interstellar space.

Yep. With control over the Relay network and their foes being locked into the mass effect field tech paradigm, every enemy the Reapers fought before the current cycle could be casually defeated in detail.

Isn't the point of it also that the Reapers control the network, and can turn it on or off at will? Making every cycle until the current one a complete curbstomp. And also that it more subtly binds the affected species to a certain paradigm of tech progression ... one that ensures they don't...